After 10 years of work, the principal investigator of the Laboratory of Cellular Metabolism and Bioenergetics of the University of Chile, Doctor in Biomedical Sciences Julio Cesar Cardenas, published in the journal Cell Reports a way to curb manipulation of cells tumor in breast cancer and prostate cancer, after tests on mice and human cells.
The finding had such an impact in the scientific community that the University of California Santa Barbara invited the Chilean researcher to conduct tests in their labs to finally be able to conduct clinical trials in humans.
Cardenas discovery focuses on how to stop the production of calcium at cellular level to prevent the proliferation of cancer cells. For this, he uses a molecule from a marine sponge of Polynesia, which allows slow production of calcium killing cancer cells. Healthy cells do not die as they accumulate energy.
To test his theory, Cardenas said that he conducted tests on human cells in vitro and in animal models (mice) for 7 years. In this way, he was able to decrease 50% of tumor growth in both types of cancers.
Tests in mice with a synthetic compound that copies that from the Polynesian sponge, which was created by the University of California, have been developed for a month to determine adverse reactions, toxicity and doses. Human trials, says the researcher, would be finally possible, after 10 years.
Source: Agencia ID