A new study has shown the impact of physical activity in patients with arrhythmogenic right ventricular dysplasia (ARVD), a type of cardiomyopathy characterized by ventricular arrhythmias and heart failure. The results have been published in the Journal of Cardiovascular Electrophysiology.
ARVD is one of the main causes of sudden death in young people and athletes and has a variable phenotype that can be determined by environmental factors.
The group of the Center of Biomedical Research in Network for Cardiovascular Diseases (CIBERCV) at the Virgen de la Victoria Hospital in Malaga, led by Manuel Jiménez Navarro, has concluded that dynamic exercise in patients with high-risk cardiomyopathy could be directly associated to early onset of arrhythmogenic ventricular dysplasia, greater severity of the disease, and to right ventricular systolic dysfunction
For this study, data on physical activity performed by patients at the time of being diagnosed with the disease was recorded. The intensity was classified according to the average frequency of weekly sessions of physical exercise in the ten years prior to the manifestation of the disease, in the following groups: high/competitive (more than 3 hours a week); moderate (from 1 to 3 hours); and inactive, with less than 1 hour.
In this way, the first important arrhythmic event and the onset of severe right ventricular dysfunction manifested earlier in the high intensity exercise group, followed by the moderate intensity group, while in the low or inactive group manifested later.
“We therefore conclude that dynamic exercise could be directly associated with the severity of the phenotype in relation to the precocity of major ventricular arrhythmic events and systolic dysfunction of the right ventricle in patients with high-risk cardiomyopathy,” the researchers said.