{"id":13454,"date":"2014-11-05T10:55:57","date_gmt":"2014-11-05T16:55:57","guid":{"rendered":"http:\/\/www.salud.carlosslim.org\/english2\/?p=13454"},"modified":"2014-11-06T17:18:44","modified_gmt":"2014-11-06T23:18:44","slug":"compounds-in-microalgae-could-prevent-inflammatory-cancers","status":"publish","type":"post","link":"http:\/\/www.salud.carlosslim.org\/english2\/compounds-in-microalgae-could-prevent-inflammatory-cancers\/","title":{"rendered":"Compounds in Microalgae Could Prevent Inflammatory Cancers"},"content":{"rendered":"

\"alga\"Scientific research group in Molecular and Applied Pharmacology (Farmolap) at the University of Seville in Spain have discovered that certain molecules contained in microalgae possess highly anti-inflammatory properties<\/strong>. These molecules, known as oxylipins<\/strong>, are derived from linolenic and linoleic acids; which are essential fatty acids that are not produced by the human body and must be acquired through diet.<\/p>\n

Though a bioassay-guided process, scientists evaluated isolated pure compounds from various microalgae extracts<\/strong>, to confirm anti-inflammatory responses<\/strong> in cell and animal models. The researchers found that the compounds have indeed highly anti-inflammatory properties and the capacity of preventing diseases like cancer caused by inflammatory conditions of the intestinal and skin epithelium<\/strong>.<\/p>\n

Microalgae are unicellular organisms that have been studied extensively, but their biotechnological research for potential applications in the energy, food and pharmaceutical industries is very recent.<\/p>\n

The use of oxylipins has been patented by the University of Seville, the Technological Institute of the Canary Islands, University of Cadiz and the company BMT. The authors explain that this patent could lead to the development of drugs or functional foods to prevent colon or skin cancer, and prevent relapses.<\/p>\n

“With these molecules called oxylipins, derived from the oxidation of polyunsaturated fatty acids, could be possible reducing the occurrence of colon tumors associated with ulcerative colitis or improve prognosis in a diagnosed cancer, reducing the inflammatory component,”<\/em> says Virginia Motilva, researcher responsible of Farmolap group.<\/p>\n

However, the researcher acknowledged that although oxylipins have produced satisfactory results in animal tests, it is necessary to conduct more pre-clinical studies before starting human trials.<\/p>\n

Motilva explained that clinical trials costs are very high. Therefore she considers necessary a partnership with a laboratory interested in licensing the molecules, in order to financing clinical trials phases 1 (safety) and 2 (efficacy). So far, a company from the United States has shown interest in this development.<\/p>\n

Farmolap Group is also developing more projects involving the study of other biomolecules in models of inflammation associated with skin or intestinal cancer<\/strong>. They are currently working on the Polfanat-II project, which aims to profoundly study the use of polyphenols — organic molecules with healthy properties, such as red wine\u2019s resveratrol.<\/p>\n

The project is coordinated by the University of Seville with the collaboration of the Autonomous University of the State of Hidalgo (UAEH), Mexico, which provides polyphenols isolated from marine invertebrates or plants endemic to Mexico.<\/p>\n

Clinicians at the University of Valencia are also collaborating to this project by studying the effects of polyphenols on human skin and intestinal biopsies. Furthermore, other biotechnological companies interested in exchanging molecular and chemical studies, such as Bionaturis, are participating.<\/p>\n

Through:<\/strong> Infosalus<\/em><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Scientific research group in Molecular and Applied Pharmacology (Farmolap) at the University of Seville in Spain have discovered that certain molecules contained in microalgae possess highly anti-inflammatory properties. These molecules, known as oxylipins, are derived from linolenic and linoleic acids; which are essential fatty acids that are not produced by the human body and must …<\/p>\n","protected":false},"author":1,"featured_media":13475,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[3],"tags":[15],"class_list":["post-13454","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualidad-en-la-salud","tag-casalud","cat-3-id","has_thumb"],"_links":{"self":[{"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/posts\/13454","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/comments?post=13454"}],"version-history":[{"count":2,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/posts\/13454\/revisions"}],"predecessor-version":[{"id":13476,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/posts\/13454\/revisions\/13476"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/media\/13475"}],"wp:attachment":[{"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/media?parent=13454"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/categories?post=13454"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/tags?post=13454"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}