{"id":23766,"date":"2018-09-05T13:00:53","date_gmt":"2018-09-05T19:00:53","guid":{"rendered":"http:\/\/www.salud.carlosslim.org\/english2\/?p=23766"},"modified":"2018-09-06T13:06:49","modified_gmt":"2018-09-06T19:06:49","slug":"insulin-related-to-an-increased-risk-of-fractures-in-type-2-diabetes","status":"publish","type":"post","link":"http:\/\/www.salud.carlosslim.org\/english2\/insulin-related-to-an-increased-risk-of-fractures-in-type-2-diabetes\/","title":{"rendered":"Insulin related to an increased risk of fractures in type 2 diabetes"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-23782\" src=\"http:\/\/www.salud.carlosslim.org\/english2\/wp-content\/uploads\/2018\/09\/vinculo-uso-insulina-mayor-riesgo-fracturas-diabetes-2.2.jpg\" alt=\"\" width=\"196\" height=\"130\" srcset=\"http:\/\/www.salud.carlosslim.org\/english2\/wp-content\/uploads\/2018\/09\/vinculo-uso-insulina-mayor-riesgo-fracturas-diabetes-2.2.jpg 600w, http:\/\/www.salud.carlosslim.org\/english2\/wp-content\/uploads\/2018\/09\/vinculo-uso-insulina-mayor-riesgo-fracturas-diabetes-2.2-300x199.jpg 300w, http:\/\/www.salud.carlosslim.org\/english2\/wp-content\/uploads\/2018\/09\/vinculo-uso-insulina-mayor-riesgo-fracturas-diabetes-2.2-250x166.jpg 250w\" sizes=\"auto, (max-width: 196px) 100vw, 196px\" \/>Spanish researchers <strong>found a link between the use of therapies with insulin and also the combination of metformin and sulfonylurea and increased bone fragility in patients with type 2 diabetes mellitus<\/strong>. After analyzing the data of more than 12,200 patients, no significant association was found between the increased risk of fracture and another antidiabetic drug.<\/p>\n<p>Researchers at the Centers for Biomedical Research in Network for Fragility and Healthy Aging (CIBERFES) and for Diabetes and Associated Metabolic Diseases (CIBERDEM) <strong>have linked the use of insulin treatments with an increased risk of fractures among patients with type 2 diabetes mellitus (DM2)<\/strong>.<\/p>\n<p>The study was led by researches Daniel Prieto-Alhambra, of the University Institute for Research in Primary Care (IDIAPJGol); Adolfo D\u00edez P\u00e9rez, of the <em>Hospital del Mar<\/em> Institute for Medical Research (IMIM;, and D\u00eddac Mauricio, of the Hospital de Santa Creu i Sant Pau. The research, published in the journal <em>Osteoporosis International<\/em>, shows that <strong>there is an increased risk of bone fracture when patients are under insulin therapy in comparison with other hypoglycemic treatments<\/strong>.<\/p>\n<p>Patients with type 2 diabetes have an increased risk of fragility fractures, and antidiabetic therapies may contribute for this to happen. \u201c<strong><em>Our objective has been to qualify the fracture risk associated with the different antidiabetic treatments usually prescribed to patients with DM2<\/em><\/strong>,&#8221; explains Prieto-Alhambra.<\/p>\n<p>In this way, the <strong>work takes into consideration the use of all antidiabetic drugs administered in the six months prior to the start date<\/strong>, comparing it with monotherapy with metformin (MTF), the most commonly used drug for this condition.<\/p>\n<p><strong>Insulin therapy and the combination of MTF and sulfonylurea (SU) were associated with a higher risk of fracture<\/strong> than MTF monotherapy in patients with DM2, which implies that the <strong>risk of fracture should be considered when a hypoglycemic medication is introduced as part of the treatment for DM2<\/strong>.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Source: <\/strong><em>SINC<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Spanish researchers found a link between the use of therapies with insulin and also the combination of metformin and sulfonylurea and increased bone fragility in patients with type 2 diabetes mellitus. After analyzing the data of more than 12,200 patients, no significant association was found between the increased risk of fracture and another antidiabetic drug. &#8230;<\/p>\n","protected":false},"author":7,"featured_media":23782,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[3],"tags":[15],"class_list":["post-23766","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualidad-en-la-salud","tag-casalud","cat-3-id","has_thumb"],"_links":{"self":[{"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/posts\/23766","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/comments?post=23766"}],"version-history":[{"count":4,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/posts\/23766\/revisions"}],"predecessor-version":[{"id":23783,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/posts\/23766\/revisions\/23783"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/media\/23782"}],"wp:attachment":[{"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/media?parent=23766"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/categories?post=23766"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/tags?post=23766"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}