{"id":25002,"date":"2019-03-03T12:00:56","date_gmt":"2019-03-03T18:00:56","guid":{"rendered":"http:\/\/www.salud.carlosslim.org\/english2\/?p=25002"},"modified":"2019-03-05T18:40:44","modified_gmt":"2019-03-06T00:40:44","slug":"scientists-are-getting-ready-to-commercialize-first-personalized-vaccine-against-cancer","status":"publish","type":"post","link":"http:\/\/www.salud.carlosslim.org\/english2\/scientists-are-getting-ready-to-commercialize-first-personalized-vaccine-against-cancer\/","title":{"rendered":"Scientists are getting ready to commercialize first personalized vaccine against cancer"},"content":{"rendered":"<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-25040\" src=\"http:\/\/www.salud.carlosslim.org\/english2\/wp-content\/uploads\/2019\/03\/vacuna-cancer.jpg\" alt=\"\" width=\"196\" height=\"130\" srcset=\"http:\/\/www.salud.carlosslim.org\/english2\/wp-content\/uploads\/2019\/03\/vacuna-cancer.jpg 600w, http:\/\/www.salud.carlosslim.org\/english2\/wp-content\/uploads\/2019\/03\/vacuna-cancer-300x199.jpg 300w, http:\/\/www.salud.carlosslim.org\/english2\/wp-content\/uploads\/2019\/03\/vacuna-cancer-250x166.jpg 250w\" sizes=\"auto, (max-width: 196px) 100vw, 196px\" \/>Scientists are about to commercialize the first personalized vaccine against cancer. If it works as expected, the vaccine, which stimulates a person&#8217;s immune system to identify the tumor from its unique mutations, could effectively stop many cancers<\/strong>.<\/p>\n<p>Unlike conventional chemotherapies, by using the body&#8217;s natural defenses to selectively destroy only tumor cells, the <strong>vaccine limits the damage caused to healthy cells<\/strong>. Attacking immune cells could also detect any missing cancer cells after the initial treatment.<\/p>\n<p>The <strong>possibility of a vaccine of this style began to take shape in 2008, five years after the completion of the <em>Human Genome Project<\/em><\/strong>, when geneticists published the first cancer cell sequence.<\/p>\n<p>Soon after, they began comparing the DNA of tumor cells with that of healthy cells. These comparisons confirmed that <strong>all cancer cells contain hundreds, if not thousands, of specific mutations, most of which are unique to each tumor<\/strong>.<\/p>\n<p>A few years later, <strong>a German company called <em>BioNTech<\/em> presented convincing evidence that a vaccine with six copies of these mutations could activate the body&#8217;s immune system to produce the T cells prepared to search, attack and destroy all the cancer cells<\/strong> present in the body.<\/p>\n<p>In December 2017, <em>BioNTech<\/em> began a large trial of the vaccine in cancer patients, in collaboration with the biotech giant <em>Genentech<\/em>. This <strong>ongoing experiment is aimed at 10 types of solid cancers and is expected to include more than 560 patients from around the world<\/strong>.<\/p>\n<p>Both companies are <strong>designing new manufacturing techniques to produce thousands of personalized vaccines economically and quickly<\/strong>. This will be complicated because to create the vaccine it is necessary a biopsy of the patient&#8217;s tumor, sequence and analyze its DNA, and produce it base on that information. As soon the vaccine is finished, it has to be delivered quickly to the hospital; because delays could be deadly for the waiting patient.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Source: <\/strong><em>Agencia ID<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists are about to commercialize the first personalized vaccine against cancer. If it works as expected, the vaccine, which stimulates a person&#8217;s immune system to identify the tumor from its unique mutations, could effectively stop many cancers. Unlike conventional chemotherapies, by using the body&#8217;s natural defenses to selectively destroy only tumor cells, the vaccine limits &#8230;<\/p>\n","protected":false},"author":7,"featured_media":25040,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[3],"tags":[15,12],"class_list":["post-25002","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualidad-en-la-salud","tag-casalud","tag-genomica","cat-3-id","has_thumb"],"_links":{"self":[{"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/posts\/25002","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/comments?post=25002"}],"version-history":[{"count":4,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/posts\/25002\/revisions"}],"predecessor-version":[{"id":25041,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/posts\/25002\/revisions\/25041"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/media\/25040"}],"wp:attachment":[{"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/media?parent=25002"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/categories?post=25002"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.salud.carlosslim.org\/english2\/wp-json\/wp\/v2\/tags?post=25002"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}